Flash Point: 204.8°F/96°C
Odor: Woody and floral
Cas#: 7212 – 44 - 4
Molecular Formula: C15H26O
Inhibits growth of leishmaniasis
Anti-parasitic: Treatment of parasitic diseases, such as those caused by helminths, amoeba, ectoparasites, parasitic fungi, and protozoa, among others
Antifungal: Treats and prevents mycoses such as athlete's foot, ringworm, candidiasis, serious systemic infections such as cryptococcal meningitis, and others
Antimicrobial: Host defense peptides
Anxiolytic: Reduce anxiety
Nerolidol, also known as peruviol and penetrol, is a sesquiterpene naturally occurring found in the essential oils of many types of plants and flowers.1 As a sesquiterpene,2 it is more aromatic and less volatile than monoterpenes and other evaporative substances. Nerolidol contains two isomers, cis and trans, which differ in the geometry of the central double bond.
Nerolidol is found in neroli, ginger, jasmine, lavender, tea tree, lemongrass, and cannabis. Nerolidol has a mild, delicate odor that has floral, apple, rose, green, and citrus-like nuances. Nerolidol’s flavor has been described as green, floral and woody with citrus and melon notes. Due to its complex aroma, nerolidol is commonly used as a flavoring agent and in perfumery.
As one of the rare substances produced by plants in response to insect attacks, nerolidol has been studied for its antiparasitic,3 antifungal, antibacterial, anxiolytic, and antioxidant properties. Nerolidol synergistically helps to destroy more bacterial pathogens4 than the antibiotic drugs alone, improving the efficacy of antibiotics. Nerolidol is currently under testing as a skin penetration enhancer5 for the transdermal delivery of therapeutic drugs. It is also known to produce a sedative effect,6 making nerolidol a promising anti-anxiety compound.7
Nerolidol is a minor component in the terpene profiles of many cannabis strains, including Royal Jack Automatic, Royal Cookies, Jack Herer, Blue Dream, Black Lime, Chemdawg, and Skywalker OG.
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