Borneol is one of the most popular terpenes used in the perfume industry due to its cool, minty, and spicy scent. The application of borneol far outreaches its cosmetic benefits though, and has an established history of use in a variety of healing capacities.
Borneol is most commonly found in camphor but can also be found in a multitude of plants around the world such as ginger, thyme, rosemary, sage, marjoram, cardamom, cinnamon, mint, nutmeg, sagebrush, tarragon, turmeric, wormwood, mugwort, sunflowers, artemisia, and cannabis. It has been used in Chinese medicine to treat chronic and acute pain since roughly 475 – 221 BC as what is known as “moxa,” which is compounded from mugwort.
Modern science continues to confirm that this terpene has powerful healing applications such as the systemic and topical1 use treat pain without drowsiness,2 unlike many western pain relief medications. Borneol also has significant medicinal and therapeutic implications in cancer treatment,3 as an anti-inflammatory,4 cardiovascular treatment (anti-coagulant),5 antioxidant, neuroprotective (potential prevention and treatment of Alzheimer’s Disease),6 antiseptic, bronchodilation, gingivitis treatment,7 and digestive tract facilitator. Borneol also has therapeutic applications in the treatment of anxiety, mental clarity and energy, memory retention, and overall wellness.
What’s more, borneol has been found to have compound “synergistic effects” when combined with other terpenes, cannabinoids, and medications because it lowers the blood-brain barrier8 which allows greater absorption of other medicines a patient might receive.9
Borneol can be found in significant amount in cannabis plants such as OG Kush, Amnesia Haze, Golden Haze, K13 Haze, Gold Country, Afgoo, Coconut Goji Berry, Sour Diesel, and Girl Scout Cookies.
Borneol has been used for analgesia and anesthesia in traditional Chinese and Japanese medicine. It is found in the essential oils of medicinal plants, including valerian. It has been researched for its inhibitory effects in diabetic rats, showing potential against hyperglycemia, hyperlipidemia, and oxidative stress.
Perhaps one of the most exciting potential medical applications for borneol is treating cerebrovascular conditions like ischemic stroke. Research indicates that borneol may have some efficacy in regulating the permeability of the blood-brain barrier (BBB). Clinical trials have been conducted to measure cerebral blood flow under the influence of borneol.
Borneol’s 'orifice-opening' or BBB-opening effect can make it easier for medications to cross the blood-brain barrier. Medical researchers are still working to understand how borneol fits into the treatment of brain conditions and other physiological conditions. Its ability to regulate protein expression and affect endothelial cells making up the BBB are also hopeful signs for its future effectiveness in brain cancer treatment.
Borneol may also be helpful in future treatments for brain tumors, specifically gliomas, and cancers involving SH-SY5Y cells (human neuroblastoma cells). By regulating the blood-brain barrier function, borneol improves drug delivery and brain distribution.
Lab Effects is a trusted source for all categories of terpenes (CDTs, BDTS, Flavors, Therapeutics, water-soluble, flowable powders, etc.) available in every format suitable for various manufacturing processes. Broneol has shown much therapeutic potential for medical applications in experimental studies. Isolated terpenes purchased from Lab Effects are guaranteed pure, 100% botanically derived, and free from chemical adulterants such as synthetic flavorants, industrial odorizers, solvents, pesticides, and metals.
Borneol is used in many personal care products to achieve a cooling effect. It can act as a TRPM8 agonist, triggering the cold sensor in humans that typically reacts to low temperatures. This could make it useful when creating topicals with a cooling effect. The same mechanism can also encourage tear production, which means borneol might someday be used in the treatment of dry eye syndrome.
Borneol has also been used for centuries in plant essential oil form to treat everything from wounds to skin irritation to headaches. Although everything about how borneol can affect any given physiological process is not known, great strides are being made in medical research. One great benefit of borneol is its ability to act as an analgesic without the common adverse effects of drowsiness or stupor.
Borneol can be good for you in the same way any chemical compound with beneficial effects can be good for you—all things in moderation and in accordance with safety recommendations. With that caveat out of the way, borneol has been known to help people with anxiety and pain, mental clarity and memory retention issues, and energy and well-being. In the right amounts, with the right delivery system, borneol could be a fantastic tool for general wellness. In medicine, studies indicate that borneol may be useful in treating heart disease, brain tumors, and more. But, more research is needed.
Borneol is safe in herbal medicine, where it has been used for centuries for its analgesic effects. Pharmaceutical forms can be expected to be "safe" within the framework of medical science. Borneol terpenes purchased to use as additives are safe when used correctly.
Keep in mind borneol is a volatile chemical compound that reacts as a highly flammable solid, liquid, and vapor with a flare-burning effect. If large amounts of purified borneol are improperly stored or transported, fire can occur with explosive violence. This is why it is critical to only use borneol as indicated by the manufacturer and to obtain borneol from reputable sources that can ensure the purity and safety of their products.
Borneol is found in the leaves of the Philippine herbal flowering shrub Blumea balsamifera, also known as Nagal camphor or Sambong. It can also be found in pine trees, under the bark or in broken fresh branches of camphor trees, and the hardwood Dryobalanops aromatica Gaertner, commonly sold as Kapur.
1. https://www.ncbi.nlm.nih.gov/pubmed/28396565
2. https://www.hindawi.com/journals/tswj/2013/808460/abs/
3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658975/
4. https://www.ncbi.nlm.nih.gov/pubmed/12473382
5. https://www.ncbi.nlm.nih.gov/pubmed/18711769
6. https://www.tandfonline.com/doi/full/10.3109/13880209.2012.700718
7. https://www.ncbi.nlm.nih.gov/pubmed/23488631
8. https://www.sciencedirect.com/science/article/pii/S0378874115000112