Terpineol refers to a combination of four monoterpene alcohol isomers (the most common is α-terpineol). α-terpineol is a terpene alcohol isolated from natural oils such as pine, petitgrain, and cajuput oil.
α-terpineol is found in a variety of plants including lilac trees, pine trees, lime blossoms, clary sage, coriander, lemon, star anise, mandarin orange, rosemary, lavender, juniper, eucalyptus, and cannabis. It is a critical component of tea tree oil and can also be found in barbed skull cap, Lapsang souchong tea,1 a black tea from China.
α-terpineol has a pleasant aroma often compared to lilac and sometimes described as ‘forest-like.’ It is found in many household and personal products such as soaps, candles, perfumes, and lotions. It is also used in food for flavor in confections, beverages, and condiments.
Many studies support significant evidence towards α-terpineol’s antioxidant, anti-inflammatory,2 antibacterial,3 anticonvulsant,4 anti-microbial,5 anti-fungal,6 anti-proliferative,7 and anti-cancerous properties.8 Some studies also indicate that α-terpineol is an immune system stimulant, and when used in aromatherapy, it has been reported to clear the sinuses and shorten the life of the common cold. When used in combination with topical therapies, α-terpineol may enhance the permeability and effectiveness of a lipid-soluble solution.9
α-terpineol is found in a wide variety of cannabis plants, and many consumers will recognize its piney scent in many popular strains including Jack Herer, White Widow, OG Kush, and Girl Scout Cookies. It also tends to coexist alongside α-pinene, another common terpene found in cannabis, and may be overlooked due to α-pinene’s potent aroma. The presence of α-pinene in the same plant does not reduce the potency of α-terpineol in any way.
Alpha-terpineol has a high potential for antifungal activities, antioxidant activity, anti-inflammatory activity, antimicrobial activity, and more. Its anti-proliferative effects support anticancer activity, suppressing tumors via cell cycle phase arrest and blockage of NF-κB expression.
Lab Effects is a trusted source for all categories of terpenes (CDTs, BDTS, Flavors, Therapeutics, water-soluble, flowable powders, etc.) available in every format suitable for various manufacturing processes. Alpha-terpineol has shown much therapeutic potential for medical applications in experimental studies. Isolated terpenes purchased from Lab Effects are guaranteed pure, 100% botanically derived, and free from chemical adulterants such as synthetic flavorants, industrial odorizers, solvents, pesticides, and metals.
Alpha terpineol is a common ingredient in perfumes and cleaning products thanks to its pleasant scent and is a valuable ingredient in medical research, specifically cancer research. As an ingredient in cytotoxic drugs, α-terpineol helps attack human cancer cell lines, resulting in cell cycle arrest and suppression of tumor growth.
One of the benefits of α-terpineol as a potential tool for the treatment of cancer is its ability to overcome resistance factors and encourage cell death. The hope is that it can be used in cancer treatment drugs to eradicate tumor growth and fight the spread of cancer throughout the body.
Like any terpene, alpha-terpineol in its raw state can be volatile. However, when properly isolated and used as an additive, it is typically harmless and can be beneficial thanks to its biological properties that allow it to aid in human skin penetration for topicals.
α-terpineol is also utilized for its antioxidant potential, cardiovascular effects, anti-inflammatory properties, analgesic effects, antihypertensive effects, gastroprotective activity, and anti-ulcer activity. It has been researched for use as an anesthetic agent, an anticancer agent, an antiseptic agent, and a potential ingredient for anticonvulsant drugs.
Alpha-terpineol is generally accepted to smell like lilac, although some detect hints of lavender as well. Others insist it can smell faintly woodsy, piney, floral, or even citrusy. It's a common essential oil extract and one of many terpene aroma chemicals used in the perfume industry.
1. https://www.therighttea.com/lapsang-souchong-tea.html
2. https://www.ncbi.nlm.nih.gov/pubmed/22380944
3. https://www.ncbi.nlm.nih.gov/pubmed/25372394
4. https://www.tandfonline.com/doi/full/10.1080/13880200601028388
5. https://academicjournals.org/article/article1379930061_Oyedemi%20et%20al.pdf
6. https://www.ncbi.nlm.nih.gov/pubmed/12969301
7. https://www.ncbi.nlm.nih.gov/pubmed/16964395?dopt=Abstract
8. http://ar.iiarjournals.org/content/30/6/1911.full
9. https://link.springer.com/article/10.1023%2FA%3A1015813803205