Myrcene is a monoterpene, the smallest of terpenes, and is found in very high concentrations in sweet basil, hops, mangos, and cannabis. Myrcene gets its name from Myrcia sphaerocarpa, a medicinal shrub from Brazil high in myrcene. Myrcene is described as having an earthy, fruity clove-like odor, but can be very pungent in higher concentrations, such as in heavily hopped beers. Not surprisingly, hops and cannabis are cousins, both members of the family Cannabaceae.
Myrcene was discovered to be the most abundant terpene in many cannabis strains. Other terpenes in the 1997 study1 include pinene, limonene, carene, humulene, bergamotene, terpinolene, and caryophyllene. For some strains, myrcene is over half the total terpene content.
Myrcene is vital in the formation of other terpenes, and it synergizes the antibiotic potential of other terpenes. Myrcene allows for more absorption of cannabinoids by the brain by changing the permeability of cell membranes. Myrcene works with cannabinoids (THC, CBD, CBG, CBC, CBN) to achieve better results than if they were isolated.
Rumors that eating a ripe mango before smoking will enhance your high have been around since the 1970s. Steep Hill Labs,3 a major cannabis testing laboratory in the Bay Area, confirmed this belief. They reported that most people experience an increased effect from cannabis by eating a fresh mango 45 minutes before inhaling or consuming cannabinoids. The myrcene found in mangoes is the main contributing factor to this effect. These “overlapping synergies” between myrcene and other terpenes with various cannabinoids, is known as the entourage effect.2
Myrcene has been found to block the cancer-causing effects of aflatoxins travel to many of our food sources from fungi.3 Myrcene’s inhibition of the liver enzyme CYP2B1 is responsible for these anti-mutagen effects. Myrcene also mitigates DNA damage from toxins such as t-butyl-hydroperoxide.4 Myrcene has also been used for many years as a folk remedy for hypertension, diabetes, diarrhea, and dysentery.
Top cannabis strains containing myrcene include OG Kush, Remedy, 9 Pound Hammer, Grape Ape, FPOG, AK-47, Granddaddy Purple, Blue Dream, Tangie, and Harlequin.
Myrcene is known to have antioxidant effects, including radical scavenging activity. Its antioxidant capacity has been the subject of studies that included myrcene dosing in rats with high lipid profiles, which showed the myrcene’s activity and its positive effects on rat lipid levels. Additional studies must be conducted to see if these biological effects will translate to improving human health. Studies focusing on human cancer cell lines exposed to myrcene are very promising. The activity B-myrcene exerted was cytotoxic, or anti-cancer, paving the way for future studies into the use of myrcene in humans as a cancer-fighting agent.
Lab Effects is a trusted source for all terpene categories (CDTs, BDTs, flavors, therapeutics, water-soluble, flowable powders, etc.) and is available in every format suitable for various manufacturing processes. Myrcene has shown much therapeutic potential for medical applications in experimental studies. Isolated terpenes purchased from Lab Effects are guaranteed pure, 100% botanically derived, and free from chemical adulterants such as synthetic flavorants, industrial odorizers, solvents, pesticides, and metals.
Animal studies using rats with arthritis showed a reduction in neuropathic pain. Another study of pain in mice showed that myrcene helped to reduce the perception of acute pain by providing analgesic effects. Myrcene has also been shown to have a range of positive therapeutic effects in humans. Some are self-reported as cannabis experience with strains that have specific terpene profiles, and the claimed therapeutic properties range from pain relief to better sleep to mood elevation and anti-anxiety effects.
Multiple plant species like hops and lemongrass, but most notably Cannabis sativa L., have high myrcene content, with levels above 65%. While every cannabis strain is now a hybrid strain, sativa-dominant strains may have higher than usual average myrcene levels.
Myrcene has been shown to have both anxiolytic and sedative effects, which can promote better, healthier sleep patterns as well as duration of sleep cycles. For people with chronic pain, B-myrcene has been shown to provide an anti-inflammatory effect and pain relief, which can also help with sleep problems. Along with limonene, myrcene has been shown to help with insomnia. Both chemical compounds can improve the speed at which you fall asleep, the quality of your sleep, and how long you stay asleep.